Nano-Bio Interactions: Curcumin Positioning on Native and Modified Cellulose Fibers
Keywords:
Curcumin, Cellulose Nanofiber, Molecular Docking, Acetylation, Methylation, Drug DeliveryAbstract
Cellulose nanofibers have attracted much attention because of their high potential for adaptive drug delivery systems. In this study, the binding affinity of curcumin to native, acetylated and methylated 10-monomer fibers was compared using molecular docking methods. Given the stronger interaction of acetylated fibers with curcumin, these fibers are expected to replace less efficient carriers, thereby improving the drug delivery of curcumin.
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