مروری بر خواص و کاربردهای کورکومین و نانوشکل های آن
Keywords:
زردچوبه, کورکومین, نانوکورکومینAbstract
با توجه به خواص دارویی و متنوع زردچوبه، در صنایع درمانی، دارویی، غذایی، آرایشی و بهداشتی و رژیم غذایی به خوبی شناخته شده است. این گیاه به دلیل خواص متعددی که دارد از جمله اثرات ترمیم کننده زخم، ضد التهاب، آنتی اکسیدان، ضد میکروبی، محافظ سلولی، ضد پیری، ضد سرطان و اثرات تعدیل کننده سیستم ایمنی اهمیت پیدا کرده است. اگرچه اثر درمانی طبیعی زردچوبه در 2500 سال قبل از میلاد برای هندی ها شناخته شده بود، تقاضای جهانی برای زردچوبه اخیراً افزایش یافته است. یکی از دلایل اصلی فعالیت های سودمند زردچوبه وجود ترکیب پلی فنلی زرد رنگ به نام کورکومین است. مطالعات زیادی در مورد خواص مختلف کورکومین و مشتقات آن انجام شده است. کورکومین علیرغم فراهمی زیستی کم، به طور موثر برای درمان بسیاری از بیماری ها مانند بیماری های قلبی عروقی و عصبی، دیابت، آرتریت و سرطان استفاده می شود. ظهور نانوبیوتکنولوژی فرصت های گسترده ای را برای کشف و گسترش استفاده از کورکومین در زمینه پزشکی باز کرده است. نانوفرمولاسیون‌های با استفاده از کورکومین و مشتقات آن به طراحی روش‌های درمانی جدید، به‌ویژه در سرطان، به دلیل زیست‌دسترسی و حلالیت بهتر نانوکورکومین در مقایسه با کورکومین طبیعی کمک کردند. این بررسی به کاربردهای مختلف کورکومین و نانوذرات کورکومین آن می پردازد و به طور گسترده تلاش می کند تا بفهمد که چگونه بر وضعیت بدن انسان تأثیر می گذارد.
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