پیشرفتهای نوین در مهندسی مواد دوبعدی: از گرافن تا MXenes و کاربردهای آینده
Keywords:
مواد دوبعدی, گرافن, MXenes, دیکلکوژنیدهای فلزات واسطهAbstract
مواد دوبعدی (2D)طی دو دهه گذشته به عنوان یکی از مهمترین کلاسهای مواد نوین مورد توجه گسترده محققان قرار گرفتهاند. از زمان کشف گرافن در سال 2004، خانواده بزرگی از مواد دوبعدی شامل دیکلکوژنیدهای فلزات واسطه (TMDs)، MXenes، نیترید بور ششضلعی (h-BN)و سایر ساختارهای لایهای توسعه یافتهاند. این مواد به دلیل خواص منحصر به فردی نظیر مساحت سطح بالا، هدایت الکتریکی و حرارتی استثنایی، انعطافپذیری مکانیکی، و قابلیت تنظیم خواص الکترونیکی، کاربردهای گستردهای در زمینههای ذخیرهسازی انرژی، کاتالیز، الکترونیک، و زیستپزشکی پیدا کردهاند. این مقاله مروری جامع به بررسی آخرین پیشرفتها در زمینه مهندسی مواد دوبعدی میپردازد. در ابتدا، روشهای سنتز مقیاسپذیر شامل رسوبگذاری شیمیایی بخار (CVD)، تقشر مایع، و سنتز شیمیایی مرطوب بررسی میشود. سپس، خواص و کاربردهای گرافن و مشتقات آن، MXenes )بهویژه(Ti3C2Tx ، و TMDs مورد تحلیل قرار میگیرد. کاربردهای این مواد در باتریهای یونی، ابرخازنها، کاتالیزگرهای تکامل هیدروژن، و سیستمهای الکترونیکی انعطافپذیر نیز بررسی میشود. در نهایت، چالشهای موجود و چشمانداز آینده این حوزه تحقیقاتی مورد بحث قرار میگیرد. نتایج نشان میدهد که مواد دوبعدی پتانسیل بالایی برای انقلاب در فناوریهای انرژی پاک و الکترونیک نسل آینده دارند.
Downloads
References
1. Novoselov, K. S., Mishchenko, A., Carvalho, A., & Castro Neto, A. H. (2016). 2D
materials and van der Waals heterostructures. Science, 353(6298), aac9439.
2. Novoselov, K. S., Geim, A. K., Morozov, S. V., Jiang, D., Zhang, Y., Dubonos, S.
V., ... & Firsov, A. A. (2004). Electric field effect in atomically thin carbon films.
Science, 306(5696), 666-669.
3. Anasori, B., & Gogotsi, Y. (2022). MXenes: trends, growth, and future directions.
Graphene and 2D Materials, 7(3), 75-79.
4. Wang, X., Gu, W., Das, P., Li, C., Li, Z. T., Jin, J., ... & Shao, M. (2025).
Chemistry of Two-Dimensional Materials for Sustainable Energy and Catalysis.
Accounts of Materials Research, 6(1), 45-56.
https://emg.bcnf.ir 12 صفحه
5. Choi, Y., Kim, J., Lee, J., Chen, X., Seo, B., Kim, Y., ... & Park, S. (2025). Recent
Progress on 2D‐Material‐Based Smart Textiles: Materials, Methods, and
Multifunctionality. Advanced Engineering Materials, 27(1), 2500188.
6. Yang, K., Li, B., Li, Z., Wang, Y., Chen, H., Wang, C., ... & Zhang, G. (2025). The
two-dimensional materials in multidimensional applications. Materials Science and
Engineering: B, 313, 117815.
7. Zhang, Y., Zhang, L., & Zhou, C. (2013). Review of chemical vapor deposition of
graphene and related applications. Accounts of Chemical Research, 46(10), 2329-
2339.
8. Li, X., Cai, W., An, J., Kim, S., Nah, J., Yang, D., ... & Ruoff, R. S. (2009). Largearea synthesis of high-quality and uniform graphene films on copper foils. Science,
324(5932), 1312-1314.
9. Wang, M., Huang, M., Sha, D., Liu, B., Zhang, C., Sheng, Y., ... & Liu, Z. (2021).
Single-crystal, large-area, fold-free monolayer graphene. Nature, 596(7873), 519-
524.
10. Kang, K., Xie, S., Huang, L., Han, Y., Huang, P. Y., Mak, K. F., ... & Park, J.
(2015). High-mobility three-atom-thick semiconducting films with wafer-scale
homogeneity. Nature, 520(7549), 656-660.
11. Duong, D. L., Yun, S. J., & Lee, Y. H. (2017). van der Waals layered materials:
opportunities and challenges. ACS nano, 11(12), 11803-11830.
12. Coleman, J. N., Lotya, M., O'Neill, A., Bergin, S. D., King, P. J., Khan, U., ... &
Nicolosi, V. (2011). Two-dimensional nanosheets produced by liquid exfoliation of
layered materials. Science, 331(6017), 568-571.
13. Stankovich, S., Dikin, D. A., Piner, R. D., Kohlhaas, K. A., Kleinhammes, A., Jia,
Y., ... & Ruoff, R. S. (2007). Synthesis of graphene-based nanosheets via chemical
reduction of exfoliated graphite oxide. Carbon, 45(7), 1558-1565.
14. Paton, K. R., Varrla, E., Backes, C., Smith, R. J., Khan, U., O'Neill, A., ... &
Coleman, J. N. (2014). Scalable production of large quantities of defect-free fewlayer graphene by shear exfoliation in liquids. Nature Materials, 13(6), 624-630.
15. Abdelkader, A. M., Valles, C., Cooper, A. J., Kinloch, I. A., & Dryfe, R. A. (2014).
Alkali reduction of graphene oxide in molten halide salts: production of corrugated
graphene derivatives for high-performance supercapacitors. ACS nano, 8(11),
11225-11233.
https://emg.bcnf.ir 13 صفحه
16. Zhan, J., Zhang, Z., Qian, X., Wang, C., Xie, Z., & Qian, Y. (1998). Solvothermal
synthesis of nanocrystalline MoS2 from MoO3 and elemental sulfur. Journal of
solid state chemistry, 141(1), 270-273.
17. Deng, D., Novoselov, K. S., Fu, Q., Zheng, N., Tian, Z., & Bao, X. (2016).
Catalysis with two-dimensional materials and their heterostructures. Nature
nanotechnology, 11(3), 218-230.
18. Wang, J., Polleux, J., Lim, J., & Dunn, B. (2007). Pseudocapacitive contributions to
electrochemical energy storage in TiO2 (anatase) nanoparticles. The Journal of
Physical Chemistry C, 111(40), 14925-14931.
19. Bang, J. H., & Suslick, K. S. (2010). Applications of ultrasound to the synthesis of
nanostructured materials. Advanced materials, 22(10), 1039-1059.
20. Geim, A. K., & Novoselov, K. S. (2007). The rise of graphene. Nature materials,
6(3), 183-191.
21. Lee, C., Wei, X., Kysar, J. W., & Hone, J. (2008). Measurement of the elastic
properties and intrinsic strength of monolayer graphene. Science, 321(5887), 385-
388.
22. Castro Neto, A. H., Guinea, F., Peres, N. M., Novoselov, K. S., & Geim, A. K.
(2009). The electronic properties of graphene. Reviews of modern physics, 81(1),
109.
23. Balandin, A. A., Ghosh, S., Bao, W., Calizo, I., Teweldebrhan, D., Miao, F., &
Lau, C. N. (2008). Superior thermal conductivity of single-layer graphene. Nano
letters, 8(3), 902-907.
24. Zhu, Y., Murali, S., Cai, W., Li, X., Suk, J. W., Potts, J. R., & Ruoff, R. S. (2010).
Graphene and graphene oxide: synthesis, properties, and applications. Advanced
materials, 22(35), 3906-3924.
25. Dreyer, D. R., Park, S., Bielawski, C. W., & Ruoff, R. S. (2010). The chemistry of
graphene oxide. Chemical society reviews, 39(1), 228-240.
26. Pei, S., & Cheng, H. M. (2012). The reduction of graphene oxide. Carbon, 50(9),
3210-3228.
27. Wang, X., Li, X., Zhang, L., Yoon, Y., Weber, P. K., Wang, H., ... & Dai, H.
(2009). N-doping of graphene through electrothermal reactions with ammonia.
Science, 324(5928), 768-771.
28. Schwierz, F. (2010). Graphene transistors. Nature nanotechnology, 5(7), 487-496.
https://emg.bcnf.ir 14 صفحه
29. Stoller, M. D., Park, S., Zhu, Y., An, J., & Ruoff, R. S. (2008). Graphene-based
ultracapacitors. Nano letters, 8(10), 3498-3502.
30. Jiao, Y., Zheng, Y., Jaroniec, M., & Qiao, S. Z. (2015). Design of electrocatalysts
for oxygen-and hydrogen-involving energy conversion reactions. Chemical Society
Reviews, 44(8), 2060-2086.
31. Yang, K., Feng, L., Shi, X., & Liu, Z. (2013). Nano-graphene in biomedicine:
theranostic applications. Chemical Society Reviews, 42(2), 530-547.
32. Naguib, M., Kurtoglu, M., Presser, V., Lu, J., Niu, J., Heon, M., ... & Barsoum, M.
W. (2011). Two-dimensional nanocrystals produced by exfoliation of Ti3AlC2.
Advanced materials, 23(37), 4248-4253.
33. VahidMohammadi, A., Rosen, J., & Gogotsi, Y. (2021). The world of twodimensional carbides and nitrides (MXenes). Science, 372(6547), eabf1581.
34. Barsoum, M. W. (2013). MAX phases: properties of machinable ternary carbides
and nitrides. John Wiley & Sons.
35. Khazaei, M., Ranjbar, A., Arai, M., Sasaki, T., & Yunoki, S. (2017). Electronic
properties and applications of MXenes: a theoretical review. Journal of Materials
Chemistry C, 5(10), 2488-2503.
36. Mathis, T. S., Maleski, K., Goad, A., Sarycheva, A., Anayee, M., Foucher, A. C., ...
& Gogotsi, Y. (2021). Modified MAX phase synthesis for environmentally stable
and highly conductive Ti3C2 MXene. ACS nano, 15(4), 6420-6429.
37. Ghidiu, M., Lukatskaya, M. R., Zhao, M. Q., Gogotsi, Y., & Barsoum, M. W.
(2014). Conductive two-dimensional titanium carbide 'clay' with high volumetric
capacitance. Nature, 516(7529), 78-81.
38. Wyatt, B. C., Rosenkranz, A., & Anasori, B. (2021). 2D MXenes: tunable
mechanical and tribological properties. Advanced Materials, 33(17), 2007973.
39. Hantanasirisakul, K., & Gogotsi, Y. (2018). Electronic and optical properties of 2D
transition metal carbides and nitrides (MXenes). Advanced materials, 30(52),
1804779.
40. Samylingam, I., Kadirgama, K., Samylingam, L., Ramasamy, D., Ghazali, M. F.,
Aslfattahi, N., ... & Saidur, R. (2024). Review of Ti3C2Tx MXene Nanofluids:
Synthesis, Characterization, and Applications. Engineering, Technology & Applied
Science Research, 14(3), 14189-1413.
https://emg.bcnf.ir 15 صفحه
41. Lukatskaya, M. R., Kota, S., Lin, Z., Zhao, M. Q., Shpigel, N., Levi, M. D., ... &
Gogotsi, Y. (2017). Ultra-high-rate pseudocapacitive energy storage in twodimensional transition metal carbides. Nature Energy, 2(8), 17105.
42. Mashtalir, O., Naguib, M., Mochalin, V. N., Dall'Agnese, Y., Heon, M., Barsoum,
M. W., & Gogotsi, Y. (2013). Intercalation and delamination of layered carbides
and carbonitrides. Nature communications, 4(1), 1716.
43. Seh, Z. W., Fredrickson, K. D., Anasori, B., Kibsgaard, J., Strickler, A. L.,
Lukatskaya, M. R., ... & Vojvodic, A. (2016). Two-dimensional molybdenum
carbide (MXene) as an efficient electrocatalyst for hydrogen evolution. ACS
Energy Letters, 1(3), 589-594.
44. Dall'Agnese, Y., Taberna, P. L., Gogotsi, Y., & Simon, P. (2015). Twodimensional vanadium carbide (MXene) as positive electrode for sodium-ion
capacitors. The Journal of Physical Chemistry Letters, 6(12), 2305-2309.
45. Kamysbayev, V., Filatov, A. S., Hu, H., Rui, X., Lagunas, F., Wang, D., ... &
Talapin, D. V. (2020). Covalent surface modifications and superconductivity of
two-dimensional metal carbide MXenes. Science, 369(6506), 979-983.
46. Nemani, S. K., Zhang, B., Wyatt, B. C., Hood, Z. D., Manna, S., Khaledialidusti,
R., ... & Anasori, B. (2021). High-entropy 2D carbide MXenes: TiVNbMoC3 and
TiVCrMoC3. ACS nano, 15(8), 12815-12825.
47. Chhowalla, M., Shin, H. S., Eda, G., Li, L. J., Loh, K. P., & Zhang, H. (2013). The
chemistry of two-dimensional layered transition metal dichalcogenide nanosheets.
Nature chemistry, 5(4), 263-275.
48. Qian, X., Liu, J., Fu, L., & Li, J. (2014). Quantum spin Hall effect in twodimensional transition metal dichalcogenides. Science, 346(6215), 1344-1347.
49. Splendiani, A., Sun, L., Zhang, Y., Li, T., Kim, J., Chim, C. Y., ... & Wang, F.
(2010). Emerging photoluminescence in monolayer MoS2. Nano letters, 10(4),
1271-1275.
50. Mak, K. F., Lee, C., Hone, J., Shan, J., & Heinz, T. F. (2010). Atomically thin
MoS2: a new direct-gap semiconductor. Physical review letters, 105(13), 136805.
51. Hinnemann, B., Moses, P. G., Bonde, J., Jørgensen, K. P., Nielsen, J. H., Horch, S.,
... & Nørskov, J. K. (2005). Biomimetic hydrogen evolution: MoS2 nanoparticles
as catalyst for hydrogen evolution. Journal of the American Chemical Society,
127(15), 5308-5309.
https://emg.bcnf.ir 16 صفحه
52. Stephenson, T., Li, Z., Olsen, B., & Mitlin, D. (2014). Lithium ion battery
applications of molybdenum disulfide (MoS2) nanocomposites. Energy &
Environmental Science, 7(1), 209-231.
53. Zhao, W., Ghorannevis, Z., Chu, L., Toh, M., Kloc, C., Tan, P. H., & Eda, G.
(2013). Evolution of electronic structure in atomically thin sheets of WS2 and
WSe2. ACS nano, 7(1), 791-797.
54. Huang, S., Ling, X., Liang, L., Kong, J., Terrones, H., Meunier, V., & Dresselhaus,
M. S. (2014). Probing the interlayer coupling of twisted bilayer MoS2 using
photoluminescence spectroscopy. Nano letters, 14(10), 5500-5508.
55. Tongay, S., Sahin, H., Ko, C., Luce, A., Fan, W., Liu, K., ... & Wu, J. (2014).
Monolayer behaviour in bulk ReS2 due to electronic and vibrational decoupling.
Nature communications, 5(1), 3252.
56. Radisavljevic, B., Radenovic, A., Brivio, J., Giacometti, V., & Kis, A. (2011).
Single-layer MoS2 transistors. Nature nanotechnology, 6(3), 147-150.
57. Lopez-Sanchez, O., Lembke, D., Kayci, M., Radenovic, A., & Kis, A. (2013).
Ultrasensitive photodetectors based on monolayer MoS2. Nature nanotechnology,
8(7), 497-501.
58. Voiry, D., Salehi, M., Silva, R., Fujita, T., Chen, M., Asefa, T., ... & Chhowalla, M.
(2013). Conducting MoS2 nanosheets as catalysts for hydrogen evolution reaction.
Nano letters, 13(12), 6222-6227.
59. Simon, P., Gogotsi, Y., & Dunn, B. (2014). Where do batteries end and
supercapacitors begin? Science, 343(6176), 1210-1211.
60. El-Kady, M. F., & Kaner, R. B. (2013). Scalable fabrication of high-power
graphene micro-supercapacitors for flexible and on-chip energy storage. Nature
communications, 4(1), 1475.
61. Gogotsi, Y., & Penner, R. M. (2018). Energy storage in nanomaterials–capacitive,
pseudocapacitive, or battery-like? ACS nano, 12(3), 2081-2083.
62. Acerce, M., Voiry, D., & Chhowalla, M. (2015). Metallic 1T phase MoS2
nanosheets as supercapacitor electrode materials. Nature nanotechnology, 10(4),
313-318.
63. Nitta, N., Wu, F., Lee, J. T., & Yushin, G. (2015). Li-ion battery materials: present
and future. Materials today, 18(5), 252-264.
https://emg.bcnf.ir 17 صفحه
64. Li, N., Chen, Z., Ren, W., Li, F., & Cheng, H. M. (2012). Flexible graphene-based
lithium ion batteries with ultrafast charge and discharge rates. Proceedings of the
national academy of sciences, 109(43), 17360-17365.
65. Anasori, B., Lukatskaya, M. R., & Gogotsi, Y. (2017). 2D metal carbides and
nitrides (MXenes) for energy storage. Nature Reviews Materials, 2(2), 1-17.
66. Wang, H., Wu, Y., Yuan, X., Zeng, G., Zhou, J., Wang, X., & Chew, J. W. (2018).
Clay-inspired MXene-based electrochemical devices and photo-electrocatalyst:
state-of-the-art progresses and challenges. Advanced Materials, 30(12), 1704561.
67. Kundu, D., Talaie, E., Duffort, V., & Nazar, L. F. (2015). The emerging chemistry
of sodium ion batteries for electrochemical energy storage. Angewandte Chemie
International Edition, 54(11), 3431-3448.
68. Zhao, M. Q., Ren, C. E., Ling, Z., Lukatskaya, M. R., Zhang, C., Van Aken, K. L.,
... & Gogotsi, Y. (2015). Flexible MXene/carbon nanotube composite paper with
high volumetric capacitance. Advanced Materials, 27(2), 339-345.
69. Wen, Y., Rufford, T. E., Chen, X., Li, N., Lyu, M., Dai, L., & Wang, L. (2017).
Nitrogen-doped graphene and porous carbon derived from cotton for highperformance supercapacitors. Journal of Power Sources, 342, 535-545.
70. Zheng, Y., Jiao, Y., Jaroniec, M., & Qiao, S. Z. (2015). Advancing the
electrochemistry of the hydrogen-evolution reaction through combining experiment
and theory. Angewandte Chemie International Edition, 54(1), 52-65.
71. Jaramillo, T. F., Jørgensen, K. P., Bonde, J., Nielsen, J. H., Horch, S., &
Chorkendorff, I. (2007). Identification of active edge sites for electrochemical H2
evolution from MoS2 nanocatalysts. Science, 317(5834), 100-102.
72. Gong, K., Du, F., Xia, Z., Durstock, M., & Dai, L. (2009). Nitrogen-doped carbon
nanotube arrays with high electrocatalytic activity for oxygen reduction. Science,
323(5915), 760-764.
73. Pandey, M., Vojvodic, A., Thygesen, K. S., & Jacobsen, K. W. (2015). Electronic
structure and catalytic activity of MXenes for the hydrogen evolution reaction. The
Journal of Physical Chemistry Letters, 6(8), 1577-1585.
74. Suen, N. T., Hung, S. F., Quan, Q., Zhang, N., Xu, Y. J., & Chen, H. M. (2017).
Electrocatalysis for the oxygen evolution reaction: recent development and future
perspectives. Chemical Society Reviews, 46(2), 337-365.
https://emg.bcnf.ir 18 صفحه
75. Gong, M., Li, Y., Wang, H., Liang, Y., Wu, J. Z., Zhou, J., ... & Dai, H. (2013). An
advanced Ni–Fe layered double hydroxide electrocatalyst for water oxidation.
Journal of the American Chemical Society, 135(23), 8452-8455.
76. Zhu, Y. P., Guo, C., Zheng, Y., & Qiao, S. Z. (2017). Surface and interface
engineering of noble-metal-free electrocatalysts for efficient energy conversion
processes. Accounts of chemical research, 50(4), 915-923.
77. Li, Z., Zhuang, Z., Lv, F., Zhu, H., Zhou, L., Luo, M., ... & Mai, L. (2018). The
marriage of the FeN4 moiety and MXene boosts oxygen reduction catalysis: Fe
single atom anchored on N-doped Ti3C2 as an efficient ORR electrocatalyst.
Advanced materials, 30(43), 1803220.
78. Qiao, J., Liu, Y., Hong, F., & Zhang, J. (2014). A review of catalysts for the
electroreduction of carbon dioxide to produce low-carbon fuels. Chemical Society
Reviews, 43(2), 631-675.
79. Kumar, B., Llorente, M., Froehlich, J., Dang, T., Sathrum, A., & Kubiak, C. P.
(2012). Photochemical and photoelectrochemical reduction of CO2. Annual review
of physical chemistry, 63, 541-569.
80. Asadi, M., Kim, K., Liu, C., Addepalli, A. V., Abbasi, P., Yasaei, P., ... & SalehiKhojin, A. (2016). Nanostructured transition metal dichalcogenide electrocatalysts
for CO2 reduction in ionic liquid. Science, 353(6298), 467-470.
81. Handoko, A. D., Fredrickson, K. D., Anasori, B., Convey, K. W., Johnson, L. R.,
Gogotsi, Y., ... & Vojvodic, A. (2017). Tuning the basal plane functionalization of
two-dimensional metal carbides (MXenes) to control hydrogen evolution activity.
ACS applied energy materials, 1(1), 173-180.
82. Akinwande, D., Petrone, N., & Hone, J. (2014). Two-dimensional flexible
nanoelectronics. Nature communications, 5(1), 5678.
83. Bae, S., Kim, H., Lee, Y., Xu, X., Park, J. S., Zheng, Y., ... & Iijima, S. (2010).
Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nature
nanotechnology, 5(8), 574-578.
84. Iqbal, A., Sambyal, P., & Koo, C. M. (2020). 2D MXenes for electromagnetic
shielding: a review. Advanced functional materials, 30(47), 2000883.
85. Castellanos-Gomez, A. (2015). Why all the fuss about 2D semiconductors? Nature
Photonics, 10(4), 202-204.
https://emg.bcnf.ir 19 صفحه
86. Kang, M. S., Jang, H. J., Jo, H. J., Raja, I. S., & Han, D. W. (2024). MXene and
Xene: promising frontier beyond graphene in tissue engineering and regenerative
medicine. Nanoscale Horizons, 9(1), 93-133.
87. Chung, C., Kim, Y. K., Shin, D., Ryoo, S. R., Hong, B. H., & Min, D. H. (2013).
Biomedical applications of graphene and graphene oxide. Accounts of chemical
research, 46(10), 2211-2224.
88. Han, X., Huang, J., Lin, H., Wang, Z., Li, P., Chen, Y., ... & Huang, Y. (2018). 2D
ultrathin MXene-based drug-delivery nanoplatform for synergistic photothermal
ablation and chemotherapy of cancer. Advanced healthcare materials, 7(9),
1701394.
89. Cheng, L., Liu, J., Gu, X., Gong, H., Shi, X., Liu, T., ... & Liu, Z. (2014).
PEGylated WS2 nanosheets as a multifunctional theranostic agent for in vivo dualmodal CT/photoacoustic imaging guided photothermal therapy. Advanced
Materials, 26(12), 1886-1893.
90. Peng, X., Peng, L., Wu, C., & Xie, Y. (2014). Two dimensional nanomaterials for
flexible supercapacitors. Chemical Society Reviews, 43(10), 3303-3323.
91. Zhu, J., Yang, D., Yin, Z., Yan, Q., & Zhang, H. (2014). Graphene and graphenebased materials for energy storage applications. Small, 10(17), 3480-3498.
92. Ding, L., Wei, Y., Li, L., Zhang, T., Wang, H., Xue, J., ... & Huang, J. (2018).
MXene molecular sieving membranes for highly efficient gas separation. Nature
communications, 9(1), 155.
93. Zhu, M., Huang, Y., Deng, Q., Zhou, J., Pei, Z., Xue, Q., ... & Zhi, C. (2016).
Highly flexible, freestanding supercapacitor electrodes with enhanced performance
obtained by hybridizing polypyrrole chains with MXene. Advanced Energy
Materials, 6(21), 1600969.
94. Lin, L., Peng, H., & Liu, Z. (2019). Synthesis challenges for graphene industry.
Nature materials, 18(6), 520-524.
95. Cai, Z., Liu, B., Zou, X., & Cheng, H. M. (2018). Chemical vapor deposition
growth and applications of two-dimensional materials and their heterostructures.
Chemical reviews, 118(12), 6091-6133.